chula75's Journal

Wednesday, June 04, 2008

Cipro - investigation results.

The frequency of A. baumannii bacteremia steadily increased over 10 old age from no cases in 1987 to 0.35 cases/1000 patient-days in 1999 (Figure 1).
During the same time, susceptibilities remained relatively stable for A. baumannii debauchee isolates.
Both ampicillin-sulbactam and imipenem-cilastatin had minimal decreases from 100% susceptible in 1989-1993 to 99% susceptible in the last 4 time of life.
The system remained relatively resistant to penicillins, cephalosporins, and ciprofloxacin (Figure 2).
Clinical ending assessments illustrated no remainder between groups.
There was no deviation in time of Edward Douglas White Jr. ancestry cell numeration or fundamental measure turning to normal; clinical phrase at day 2, day 7, or end of treatment; or antibiotic-related ICU and unit size of stay (Table 2).
The cost of intervention of A. baumannii bacteremia is high regardless of antimicrobial factor, with median antibiotic costs for ampicillin-sulbactam equal to $500 (range $50-1220) compared with $1500 (range $220-7520) for imipenem-cilastatin (p=0.0002).
Median cost of hospital-ization of an ampicillin-sulbactam-treated semantic role was $30,000 (range $9600-177,000) versus $43,200 (range $13,200-178,000) for an imipenem-cilastatin-treated affected role.
Forty-four percent of imipenem-cilastatin-treated patients and 37% of ampicillin-sulbactam-treated patients received aggregation therapy with an aminoglycoside.
Logical thinking of these variables led to several interesting findings.
Patients who received imipenem-cilastatin with another broker had a significantly longer quantity segment of stay than those given monotherapy (median 57 vs 33 days, p=0.03), whereas there were no significant differences in clinical outcomes between ampicillin-sulbactam alliance and monotherapy.
Compared with patients who received ampicillin-sulbactam monotherapy, those who received imipenem-cilastatin aggregation therapy had longer ICU stays (median 36 vs 17 days, p=0.04), unit fundamental measure of stay (median 57 vs 27 days, p=0.006), and higher medical building and antibiotic costs.
Antibiotic-related segment of stay was significantly shorter (median 8 vs 13 days, p=0.008) for patients who received ampicillin-sulbactam plus an aminoglycoside compared with imipenem-cilastatin alone.
This is a part of article Cipro - investigation results. Taken from "Cipro Antibiotic" Information Blog

Labels:

0 Comments:

Post a Comment

<< Home